Apo A1

Also known as Apolipoprotein A1; Cardiac marker test. Usually done as a part of Advanced Lipid Profile or Cardiac marker lab test.

Why test for Apo A1Test at Symbion VIP Diagnostics Pathology Lab ?

Apolipoprotein A-I (Apo-A1) is a structural and functional protein that constitutes approximately 70% of the protein in HDL.

Because it is not clear whether Apo-A1 is an independent predictor of cardiovascular disease, it may be useful to be measured in conjunction with Apo-B to assess the Apo-B/Apo-A1 ratio.

A higher ratio means an increased likelihood of cholesterol deposition in arteries, leading to atherosclerosis and a higher risk of cardiovascular disease.

Low apolipoprotein A-I level

A low Apo-A1 level indicates an increased risk of cardiovascular disease, especially in the presence of an elevated apolipoprotein B (Apo-B) level. 

Other factors that are associated with low Apo A1 level include the following:

• Chronic liver disease
• Chronic kidney disease
• Smoking
• Obesity
• High triglyceride level

High apolipoprotein A-I level
High Apo-A1 levels are associated with the following:

Pregnancy

Alcohol use

Spring and summer seasons