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Mean Platelet Volume (MPV)

Mean Platelet Volume (MPV)

Mean Platelet Volume (MPV) is a part of Platelet indices and done in hemogram or CBC blood test.

Why test for Mean Platelet Volume (MPV) at Symbion VIP Diagnostics, Ahmedabad ?

Mean platelet blood volume is a blood test that measures the average number of platelets in the blood. Platelets help the blood heal wounds and prevent excessive bleeding. High or low platelet levels can be a sign of a severe condition.
The mean platelet volume (MPV) blood test is typically part of a complete blood count (CBC) test. A CBC reveals important information about the number of different blood cells in the body.

Causes of a High Mean Platelet Volume (MPV) 
A high MPV is usually a sign that there are more young platelets circulating in your bloodstream. If you have had a procedure such as major surgery, your body is using up platelets to repair the cuts to the blood vessels. In response, your bone marrow releases more of the young, larger platelets, and your MPV rises.

Evaluating a high MPV is most helpful in determining the cause of a low platelet count, and the most common cause is "destruction," or the platelets being destroyed in some way, such as by antibodies you produce (see ITP below).

A high MPV with a high platelet count, in contrast, is often due to primary or essential thrombocytosis (a condition in which the body produces too many platelets, often due to a genetic mutation), or cancer.

A high MPV with a normal platelet count suggests conditions such as hyperthyroidism, or chronic myelogenous leukemia.

Conditions that may cause an elevated MPV include :

  • Idiopathic thrombocytopenic purpura (ITP): ITP is a condition in which the immune system destroys platelets. The condition idiopathic thrombocytopenic purpura has a long name, but looking at each of the terms in ITP makes this easier to understand. Idiopathic is a term used to describe a condition of unknown cause. It is doctor lingo for "we don't have a clue" why it occurs. The root word "thrombo" refers to clot (the function of platelets) and "penia" refers to deficiency, so thrombocytopenia refers to a deficiency of platelets. Purpura is the medical term for a bruise, usually a fairly large bruise. (The term petechiae refers to small red marks on the skin (small bruises) which don't blanch when you press on them.) 
  • Blood cancers such as leukemia.
  • Non-alcoholic liver disease.
  • Genetic abnormalities in platelets.
  • Bernard-Soulier Disease (giant platelet syndrome).
  • Bone marrow stimulating drugs, such as erythropoietin or thrombopoietin.
  • Diabetes mellitus.
  • Respiratory Diseases.
  • Sepsis.
  • Hyperthyroidism.
  • Heart attack (see below).
  • Pre-eclampsia (toxemia of pregnancy) and HELLP syndrome.
  • Artificial heart valves.
  • Causes of  Low Mean Platelet Volume (MPV)
  • Possible causes of a low MPV can also vary depending on the platelet count. A low MPV with a low platelet count can point towards disorders affecting the bone marrow that slow down or decrease the production of platelets, such as a condition called aplastic anemia. A low MPV with a high platelet count often signifies an infection, inflammation, or cancer. A low MPV with a normal platelet count is common with chronic kidney failure.

Possible causes of a low MPV include:

  • Bone marrow failure (older platelets are smaller, so the MPV is low if the bone marrow isn't producing as many).
  • Splenomegaly (an enlargement of the spleen). With hypersplenism, platelets are often "sequestered" in the spleen.
  • Chronic kidney failure
  • Medications that suppress platelet formation (such as chemotherapy drugs).
  • Hypothyroidism.
  • Iron deficiency anemia.
  • HIV/AIDS.

The laboratory test results are NOT to be interpreted as results of a "stand-alone" test. The test results have to be interpreted after correlating with suitable clinical findings and additional supplemental tests/information. Your healthcare providers will explain the meaning of your tests results, based on the overall clinical scenario. For further information about these lab tests contact Symbion VIP Diagnostics pathology lab Ahmedabad at 09429410291

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Precautions : Inquire with the lab / follow your doctor's instructions

DISCLAIMER: The information contained herein should not be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. Please contact your health care provider if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

Bodakdev Branch

Bodakdev Branch

1 Springfield, Opp Bhavanagari Sweet mart, Next to Akash Tower, Judges Bungalow Road, Bodakdev, Vastrapur, Ahmedabad. 380054

Phone: 079 26856784 / 26856785

Mobile: 9429410292 / 9825065803

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Prernatirth Branch

Prernatirth Branch

G-11, Ratnadeep-2, Opp Prernatirth Derasar, Jodhpur, Satellite, Ahmedabad. 380015

Phone: 079 40060217

Mobile: 9978917670 / 7405002115

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Bopal Branch

Bopal Branch

A-1/3 Vrajvihar Complex, Near Sales India, Opp Sterling City Gate, Bopal, Ahmedabad. 380058

Phone: 02717 - 234003 / 234004

Mobile: 9374431844

Contact Person: Karan Kot

Gota Branch

Gota Branch

GF-16 Vrindavan Heights, Near SUBWAY, Opp Center Point, Savy Swaraj Road, Gota, Ahmedabad.

Phone: 079 48488412

Mobile: 9913268412 / 9687983150

Contact Person: Himmat Kot

South Bopa Branch

South Bopal Branch

GF-17 Marigold Center, Safal Parisar Road, South Bopal, Ahmedabad. 380058

Mobile: 7572881296 / 02717-463553

Contact Person: Santosh Rana

Shahibaug Branch

Shahibaug Branch

FF-1 Manibhadra Arcade, Above Jain Dairy Parlour, Opp Rajasthan Hospital Main Gate, Above Axis Bank ATM, Shahibaug, Ahmedabad.

Phone: 079 22884202

Mobile: 9935506039

Contact Person: Pritesh Patel

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Gandhinagar Branch

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Meghaninagar Branch

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Ashish Cross Road, Opp Puja Hospital, Meghaninagar, Ahmedabad. 380016

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Asarva Branch

Asarva Branch

1 Bipin Complex, Opp Cancer Hospital Gate, Asarva Ahmedabad.

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Gandhinagar Branch

Nana Chiloda Branch

Shop No.109, First Floor, Royal Arcade, Opp. Maruti Shine, Nana Chiloda, New Shahibaug, Ahmedabad. 382330

Mobile: 77779 91905 / 9935506039

Gandhinagar Branch

New Ranip Branch

Shop No 7, Ground Floor, Shukan City, Nr. Anand Party Plot, Opp. GST Crossing Road, New Ranip, Ahmedabad

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Gandhinagar Branch

New Vasna Branch

Shop No 1, Sparsh Aaron, Opp. Sparsh Arista, New Vasna, Ahmedabad. 380007

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Gandhinagar Branch

Motera Branch

A-14, Himalaya Zircon, Near ONGC Circle, Opp Ashoka Vihar jain temple, Motera, Ahmedabad. 380005

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Gandhinagar Branch

Shilaj Branch

4-Earth Rosette, Near Ashray Arise, Shilaj Ahmedabad. 380059

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Gandhinagar Branch

Godhavi Branch

11, Ground Floor, Swastik Arcade, Godhavi Ahmedabad. 382115

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